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Aminopolycarboxylic acid
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Aminopolycarboxylic acid : ウィキペディア英語版
Aminopolycarboxylic acid

An aminopolycarboxylic acid (complexone) is a compound containing one or more nitrogen atoms connected through carbon atoms to two or more carboxyl groups. Aminopolycarboxylates that have lost acidic protons (ionised), form strong complexes with metal ions. This property makes aminopolycarboxylic acids useful in a wide variety of chemical, medical, and environmental applications.〔 (pdf )〕
==Structure==
The parent of this family of ligands is the amino acid glycine, H2NCH2CO2H, in which the amino group, NH2,is separated from the carboxyl group, CO2H by a single methylene group, CH2. When the carboxyl group is deprotonated the glycinate ion can function as a bidentate ligand, binding the metal centre through the nitrogen and one of two carboxylate oxygen atoms, to form chelate complexes of metal ions.
Replacement of a hydrogen atom on the nitrogen of glycine by another acetate residue, –CH2CO2H gives iminodiacetic acid, IDA, which is a tridentate ligand. Further substitution gives nitrilotriacetic acid, NTA, which is a tetradentate ligand.〔 (pdf )〕 These compounds can be described as aminopolycarboxylates. Related ligands can be derived from other amino acids other than glycine, notably aspartic acid.
Higher denticity is achieved by linking two or more glycinate or IDA units together. EDTA contains two IDA units with the nitrogen atoms linked by two methylene groups and is hexadentate. DTPA has two CH2CH2 bridges linking three nitrogen atoms and is octadentate. TTHA〔 has ten potential donor atoms.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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